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23/02/2017

Women With Pre-Eclampsia Have Increased Risk Of Heart Disease - Research

Women who have pre-eclampsia have an increased risk of heart disease in later life, research has found.

The research, led by Keele University, found that women with pre-eclampsia during pregnancy are four times more likely to have heart failure in later life.

They also have a two-fold increase risk of coronary heart disease, stroke and death due to cardiovascular disease in later life.

The findings, involving the analysis of 22 studies and more than 6.5 million women, have been published in the Go Red for Women Spotlight collection of the journal, Circulation: Cardiovascular Quality and Outcomes.

The authors of the study are calling for better advice to be given to women about the increased risks, and the actions they can take to avoid future ill-health.

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Pensee Wu, the first author of this publication and lecturer in Obstetrics and Gynaecology at Keele University, said the study shows the risk was highest during the first 10 years after a pregnancy affected by pre-eclampsia.

"It is important that women are regularly monitored during this period for cardiovascular risk factors such as high blood pressure, high cholesterol and obesity. The risks begins to increase for coronary heart disease, heart failure and stroke within one year after giving birth, but it is highest between one to ten years after giving birth."

Last year, the authors published another paper identifying a link between pre-eclampsia in pregnancy and the development of diabetes in later life. The study showed that pre-eclampsia is independently associated with a two-fold increase in future diabetes. This increased risk was found to occur from less than one year after delivery of the baby and persisted to over ten years after birth.

The analysis was a collaboration between researchers at Keele University's Institute for Applied Clinical Science and Institute for Science & Technology in Medicine, along with Primary Care and Health Sciences, and the University Hospital of North Midlands NHS Trust.

(CD/LM)

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"Women who have pre-eclampsia have an increased risk of heart disease in later life, research has found."